10 research outputs found

    INOVASI PEMASARAN MELALUI METODE DIGITAL BAGI UMKM: KAMPOENG BATIK LAWEYAN MARKETING INNOVATION THROUGH DIGITAL METHOD FOR SMALL AND MEDIUM ENTERPRISE: KAMPOENG BATIK LAWEYAN

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    Usaha Mikro, Kecil, dan Menengah (UMKM) merupakan salah satu yang berperan sebagai penyumbang perekonomian negara. Bentuk peran UMKM ini seperti perluasan kesempatan kerja dan pembentukan produk domestik bruto. Namun dikarenakan saat ini pandemi COVID-19 sedang melanda, banyak UMKM yang terdampak oleh pandemi ini, tidak terkecuali Kampoeng Batik Laweyan. Berdasarkan hasil analisa, observasi, dan diskusi, ditemukan beberapa permasalahan bagi mitra, seperti (a) kesadaran masyarakat terkait eksistensi Kampoeng Batik Laweyan masih sangat kurang (b) menurunnya omzet mitra karena pandemi (c) mitra belum menguasai bagaimana cara melakukan pemasaran secara digital dengan baik, dan (d) mitra belum memanfaatkan media daring dengan maksimal untuk memasarkan produk-produknya. Berdasarkan masalah yang muncul, maka hal ini membuat mitra harus berinovasi dan menemukan strategi baru. Solusi yang ditemukan yaitu (a) pembuatan konten untuk meningkatkan kesadaran merek masyarakat terkait Kampoeng Batik Laweyan, dan (b) memaksimalkan media daring sebagai media untuk promosi. Dengan dilakukannya strategi digital marketing ini, kesadaran masyarakat terkait eksistensi Kampoeng Batik Laweyan semakin meningkat. Selain itu, muncul niat untuk mengunjungi ketika situasi sudah dirasa aman

    Perencanaan Pembangkit Listrik Tenaga Surya Di Pos Pengamatan Gunung Soputan

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    This planning is carried out on the basis to meet the electricity needs that must continuously deliver electricity at the observation point of Mount Soputan, this is because electricity needs are very important in seeing the movement of the volcano. This plan with a planned load of 18.04 kWh. For such loading, 20 solar panels with 200 Wp capacity are used, and 2 solar panels controllers (SCC) are used, with each SCC used for 10 solar panels. As for the batteries used as many as 3 pieces with each battery having an energy of 2.4 kWh, then for the inverter using an inverter with a power of 2650 W

    Application of Unmanned Aerial Vehicles in Emergency Medical Situations

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    Introduction One of the significant impacts on patient outcome in emergency medical situations is the response time taken for trained personnel and equipment arrival on scene. The National EMS Information System states the average response time to reach adult patients in the United States is 9.4 minutes (1). We are exploring the whether the application of Unmanned Aerial Vehicle (UAV) technology in emergency situations would shorten response time and subsequently could improve patients’ outcome In this reported on first phase (Phase 1) of an envisioned multi-stage project, we tested the ability of a UAV to properly, efficiently transport a a portable ECG device to a mock emergency site and successfully take an ECG reading when used by an untrained personnel on hand. MethodsOur UAV was a DJI Phantom 2 Vision model, a quadcopter equipped with a 14 Megapixel camera and HD video recording capabilities. The onboard camera allows for real time transmission of patient status and appearance, while the quadcopter model allows for maximum weight to lift ratio. In order to record a portable ECG, we equipped an iPhone 5 with an AliveCor Kardia mobile ECG monitor. We included an easy to use protocol for the AliveCor so that a layperson would be able to operate the machine. DataThe total flight time for 100 yards across an open field was two and a half minutes , or approximately 2 feet/second. This data shows a chi-squared distribution of 5.065, with a p-value of .01 (df=1, p\u3c.05). DiscussionDue to the statistically significant p-value, Phase 1 data demonstrates that our UAV was capable of traversing an appropriate distance in an amount of time that drastically improves upon the emergency response call time taken by traditional methods. In addition to our flight data, we were also able to properly operate the ECG and apply it to a mock patient in under 90 seconds, showing that our protocol, with instructions for usage, was clear and precise. Conclusion: This study is considered Phase 1 of a multi-stage investigation. Moving forward, we hope to improve the efficacy of our UAV, while expanding its the technological and medical capabilities, allowing it to not only carry ECG but also possibly AEDs and pharmaceuticals. Ultimately, We hope to apply such technology to emergencies in both rural and urban environments, as well as adapt it for use within the military

    Association of Hyperchloremia and Acute Kidney Injury in Pediatric Moderate and Severe Traumatic Brain Injury

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    PURPOSE: Acute kidney injury (AKI) is an established complication of adult traumatic brain injury (TBI) and known risk factor for mortality. Evidence demonstrates an association between hyperchloremia and AKI in critically ill adults but studies in children are scarce. Given frequent use of hypertonic saline in the management of pediatric TBI, we believe the incidence of hyperchloremia will be high and hypothesize that it will be associated with development of AKI. METHODS: Single-center retrospective cohort study was completed at an urban, level 1 pediatric trauma center. Children \u3e 40 weeks corrected gestational age and \u3c 21 years of age with moderate or severe TBI (presenting GCS \u3c 13) admitted between January 2016 and December 2021 were included. Primary study outcome was presence of AKI (defined by pediatric Kidney Disease: Improving Global Outcomes criteria) within 7 days of hospitalization and compared between patients with and without hyperchloremia (serum chloride ≄ 110 mEq/L). RESULTS: Fifty-two children were included. Mean age was 5.75 (S.D. 5.4) years; 60% were male (31/52); and mean presenting GCS was 6 (S.D. 2.9). Thirty-seven patients (71%) developed hyperchloremia with a mean peak chloride of 125 (S.D. 12.0) mEq/L and mean difference between peak and presenting chloride of 16 (S.D. 12.7) mEq/L. Twenty-three patients (44%) developed AKI; of those with hyperchloremia, 62% (23/37) developed AKI, while among those without hyperchloremia, 0% (0/15) developed AKI (difference 62%, 95% CI 42-82%, p \u3c 0.001). Attributable risk of hyperchloremia leading to AKI was 62.2 (95% CI 46.5-77.8, p = 0.0015). CONCLUSION: Hyperchloremia is common in the management of pediatric TBI and is associated with development of AKI. Risk appears to be associated with both the height of serum chloride and duration of hyperchloremia

    Incidence of abnormal uterine bleeding and endometrial hyperplasia in postmenopausal women treated with Pellet Hormonal Therapy

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    Objective: The objective of this study was to assess the incidence of abnormal uterine bleeding (AUB) and endometrial hyperplasia in postmenopausal women treated with non-FDA approved Pellet Hormonal Therapy (PHT) while compared with FDA approved Hormonal Therapy (FHT). Design: A retrospective cohort study was designed to compare two cohorts (PHT vs. FHT). A total of 522 postmenopausal women with menopausal symptoms were identified from the Reading Hospital Electronic Medical Record System through pharmacy coding, including 367 on PHT (estradiol [E2, 6-37.5mg] and/or testosterone [T,12-137.5 mg] pellets) and 155 on FHT. Data on demographics, initial menopausal symptoms (i.e. hot flash, vaginal dryness, decreased libido), side effects (i.e. AUB, mood swing, anxiety, breast tenderness, change in hair pattern, acne, weight gain), and treatment duration were extracted from medical records. Chi-Square test was applied to assess the difference in incidence of side effects between the two cohorts, and a multiple logistic regression was fit with covariates (HT cohort, age at the initiation of HT, Body Mass Index, duration of HT), to assess risk profile of the individual covariate. Results: Women on PHT (n=367) were significantly younger than those on FHT (n=155), with mean age (SD) of 51.04 (7.52) and 60.61 (9.56) years, respectively (p\u3c.0001). The incidence of side effects was significantly higher in PHT while compared with FHT (179 [49.5%] vs. 23 [15.3%], p\u3c.0001, odds ratio [95% CI] =5.92[3.42-10.25]). A total of 91 (58.7%) women on FHT had a hysterectomy prior to the initiation of HT, which was significantly higher than the 151 (41.4%) on PHT (p=0.0003). When examining 276 women with an intact uterus prior to HT initiation, mean (SD) duration of HT treatment in years were significantly longer in PHT group (3.11 [1.64] vs. 2.15 [2.22], p=.0023). During the treatment, 59.4% (127/214) on PHT vs. 19.4% (12/62) on FHT had at least one episode of AUB (p\u3c.0001, odds ratio [95% CI] =7.15[3.00-17.04]). Of those, 54 (27%) and 5 (7.8%) had a hysterectomy while on PHT and FHT respectively (p=.0013, odds ratio [95% CI] =3.49[1.22-9.99]), and 87(41.8%) in PHT vs. 10 (16.4%) in FHT had endometrial pathology available either from endometrial biopsy or hysterectomy. No endometrial cancer was identified in either group. There was no significant difference in incidence of endometrial hyperplasia between the two cohorts (22[25.9%] vs. 4[40.0%]), with 3(14%) in PHT vs. 0 in FHT being diagnosed with endometrial hyperplasia with atypia. A total of 201 women on PHT had lab monitoring data available, abnormal E2 and T level were detected in 52 (25.9%) and 133 (66.2%) women, respectively, who subsequently required dose adjustment. Conclusion: When compared with women on FHT, women on PHT had a significantly higher incidence of AUB and hysterectomy. It may be difficult to assess difference in incidence of endometrial hyperplasia due to relatively rare outcome and short durations of HT treatment in our study. Large scale prospective clinical trials are warranted to further investigate the safety of PHT for treating menopausal symptoms

    Heteromeric Dopamine Receptor Signaling Complexes: Emerging Neurobiology and Disease Relevance

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